Night work or the alternative system can lead to the acceleration of aging

A new study, conducted by researchers at Kings London College, and published in the facts of the National Academy, revealed that muscle cells contain ‘internal biological watches’, which organize their renewal operations, and that it would disrupt them, as in the working conditions of the night or with the shift system, lead to acceleration and weakening. The researchers used transparent infection fish, which share in about 70% of the genes with people, to accurately study this effect, and their muscle membranes are colored with a bright dye to facilitate the measurement of the muscle size and follow their functions with age. The researchers weakened the biological watch in muscle cells by adding a functional functional protein, and via monitoring these fish for two years, scientists noted that the fish that disrupted their muscle bell, smaller, less weight, less swimming, and slower at the age of two years, similar to what we see in muscle aging, or what is known as (Sarquobinia). Muscle aging, muscle aging or sarcopinia, a degenerative condition that affects muscles with age, and which gradually affects strength and physical ability, and it is supposed to start after the age of forty, and exacerbate with age, or due to environmental factors such as lack of physical activity, malnutrition and biological clock disorder. Some of the most important signs of muscle aging are the decrease in muscle mass, as the muscle fibers become in fat or sponsorship tissue, leading to poor power and endurance. The people with a slow movement, and the trouble of performing daily tasks such as promoting the chair, or transporting purchases, in addition to an imbalance, and the increase in the possibility of falling and injuries. Some of the most famous signs of this aging are chronic fatigue to a simple effort, unjustified weight loss and a decrease in general motor activity of additional signs. These symptoms not only affect the quality of life, but are also associated with an increase in the risk of chronic diseases such as diabetes, heart disease, increasing dependency rates of others, or to incur long -term care. Although major differences were not monitored in the first months of fish life, the manifestations of muscle weakening clearly appeared in the advanced era, which indicates a long -term cumulative effect of biological clock disorder. On the mechanism of this decline, the researchers said that the muscle biological watch is active at night to clean the muscle of the damaged protein due to daily use, which is an essential process of maintaining muscle mass, and when this “night interview” is disrupted, proteins are damaged, leading to muscle weakness and acceleration. The researchers emphasized that the study highlights great risks and threatens about four million varying workers in the UK alone. The damage of the night action and the lead author of the study, Jeffrey Kilo, says: “We need to realize that nightwork not only affects sleep, but that the body can affect the biological watch from the inside, even at cell level, including muscles, heart and immunity.” The researchers pointed out that preliminary studies are currently being conducted to test medicines aimed at biological clock proteins, which open the way for the development of preventative treatments against the weakening of muscles in the workers in the shift system. Professor Simon Hughes, a specialist in cell biology, said that these results show how we can discover many complicated things through simple creatures like clinics, “it’s just to make sure that what we found there also applies to people.” This study contributes to the increasing evidence of the profound impact of the biological watch in the regulation of public health, not only in the brain, but also in the muscles, and raises important questions about the need to reconsider nightworking systems, and ways to protect those who are indispensable for their work at night.