Von Filbrand disease: causes, symptoms and treatment

Von Willebrand disease under the protection of Von Filbrand is one of the genetic diseases that cause automatic bleeding, as blood does not naturally solidify due to low levels of the Von Wilbrand factor, one of the most important proteins in the blood clotting process. Important notes about the Velberland worker in the blood are one of the most important notes about the Von Felberland worker in the blood. The following: This factor is a molecular weight (molecular weight) is very high and consists of sub -units called multimers. These molecules are produced in stem cells in stem cells that produce platelets in the bone marrow. The percentage of the von fibrant worker in cases of illness varies in right cases, and estrogen and thyroid work to regulate this level of circulation. The percentage of the Von Filbrand worker increases during pregnancy 2-3 times, and the percentage also increases in cases of infection or acute physical activity. The normal level of this factor is less in people with a blood type o compared to other blood factions. The Von Filbrand worker is associated with the platelets (thrombocytes) and the tissue under the endothelial cells, as it serves as an intermediary and links to stop immediate bleeding to the blood vessels, and it also carries solidification proteins and protects them at premature dissolution in the circulation. According to laboratory tests, the types of Von Fibrand are classified into three types, in addition to the degree of severity of the disease as follows: a moderate decrease in the amount of voning worker: this type of form 80% of all cases of this disease. A qualitative problem in the quality of the Von Fibrand molecular molecule: This type of disease is about 5-20% of people. Not fully produced the Von Filbrand worker: This type is very rare, because there can be one case per million patients. Symptoms of Von Filbrand disease include symptoms of Von Filbrand, the following: Serious bleeding after any injury or after surgery, or a specific treatment for teeth. Large amounts of blood during menstruation. The incidence of blood in the urine and feces. Bruises spread in different parts of the body. Symptoms of anemia, such as fatigue, tension and shortness of breath. Causes and factors of the risk of Von Filbrand we call, while the causes and factors of the risk of von fibrend are as follows: 1. Causes of von Filbrand disease are the main cause of von Felperand disease and a mutation in one of the genes that controls the production of the Von Felperand factor, which causes a reduction in its levels. 2.. The risk of Von Filbrand is the presence of a family history of the disease, one of the most important risk factors, and it is worth noting that the Von Filbrand disease is a prevailing heritage of physical dominance, which means you need a single gay -no of one of the parents to develop diseases. It is important to know that people are rarely infected with this disease, and men and women are usually in most cases complications of the von Felperand disease. Von Felpernd disease does not cause complications, but sometimes it can: cause anemia, especially in women suffering from severe bleeding during the menstrual cycle. Swelling and pain due to regular bleeding in the joints and tissues. The diagnosis of the Von Filbrand does the doctor an extensive medical and physical examination, and there is sometimes necessary to perform a few tests as follows: The Von Wilbrand is Antigen: Through this investigation, it is possible to know the levels of the Von Wilbrand in the blood. Von Wilbrand’s activity: Through this investigation, it is possible to know how effective the Von Wilbrand worker is in the blood clotting process. The activity of the eighth clotting factor: where the levels of the eighth coagulation factor are measured in the blood, in addition to its scope of the activity. Von Wilbrand’s Multi Factor: This investigation can be determined by the Type of Von Wilbrand. The treatment of Von Filbrand There are many ways in which the Von Filbrand disease can be treated: Desmoprorys can stimulate the body to secrete more von Wilbrand worker stored in the lining of blood vessels and can be taken in the form of injection or nose spray. Alternative treatments This treatment contains injections that contain concentrated coagulation factors, one of which is the iPhone Wilbrand, and this treatment is used in the case of a non -reaction to dysoprissin. Oral contraceptive methods help steragin pills control the levels of the iPhone Wilbrand worker during menstruation, reducing the abundance of blood. The stabilizers of the strokes this medicine delay the process of decomposing lumps, which helps to bloom faster, and is usually used after surgery or tooth treatment. Fiberin stickers The adhesive contains fibrin, and it is placed directly on the wound, which increases the process of clotting and stops the bleeding faster. Prevention of Von Filbrand, there are no clear methods by which you can occur von Filbrand as it stems from genetic causes, but it is preferable to discuss the doctor before planning pregnancy in the event of a family history of the disease.