Crohn's disease: causes, symptoms and treatment
Crohn’s disease with Crohn’s disease is a chronic inflammation of the digestive system in general from the mouth to the anal opening. This inflammation spreads in an incapacitated way in all layers of the intestinal wall and is characterized by the presence of intact and natural infected areas, and can be changed with an infected one. The highlight of Crohn’s disease is usually in the third decade of life. Crohn’s disease patterns are characterized by Crohn’s disease with four patterns of different and different clinical forms, and it is as follows: 1. The inflammatory image appears in the form of pain on the lowest right side of the abdomen accompanied by diarrhea, fever and a decrease in weight. 2. The subparactic image is characterized by pain and flatulence after eating, constipation, nausea, vomiting and low weight. 3.. Hidden covered in healing appears with symptoms similar to those that characterize appendicitis, diversiculitis and through the rise of fistula. 4. Intestinal loop with another member, then the patient complains about the secretion of the opening to the skin to the urinary tract or sexual channel, and the signs of infection may also occur, and the laboratory examination in such a case indicates chronic inflammation, where red pellets are placed with high velocity in the erythrocyte seed seed testing. Disorders caused by the disease outside the intestines and Crohn’s disease may also include problems with organs from outside the intestines, such as: dermatitis. Pain in the joints. Eye problems. Kidney stones. Gallstones. Different liver disorders. Crohn’s disease increases the risk of developing major intestinal cancer, such as colon cancer or micro -organism. Symptoms of Crohn’s disease that accompany Crohn’s disease can range from moderate to very hard, and these symptoms can suddenly occur suddenly without warning. In the following, some of the symptoms characterized by Crohn’s disease stimulate: diarrhea, inflammation caused by Crohn’s disease, the cells in the affected areas in the intestinal walls, to secrete a very large amount of water and salts, and as the intestines cannot completely absorb the excess fluids, place it. The acute intestinal coffins also contribute to the production of very soft faeces, and in less severe cases the stools can be softer than usual and at a higher rate than usual, but people suffering from Crohn’s disease may suffer from the need to cover about 12 times a day, which negatively affects the quality of sleep and daily activities. The pain of the abdomen and cramps of inflammation and wounds that can cause it can swell the intestinal wall to the point that the scars are formed in its existence, and it can negatively affect the movement of the intestinal content, which can cause pain and cramps. An uncomfortable feeling causes Crohn’s disease in his middle degree an uncomfortable feeling ranging from light to moderate, and the more serious the condition is, the worse pain and can be accompanied by nausea and vomiting. Blood in the stools that move over the intestines can cause bleeding from inflamed areas, or the bowel blood itself can cause, and in such a case, the signs of blood can occur in a light red color at the ends of the toilet basin, or in red red with faeces, but the blood can be invisible. Crohn’s stomach ulcers start with a small and sporadic wounds on the surface of the walls of the intestines, and in the end these wounds become in large ulcers that penetrate deep, and sometimes they cross the walls of the intestines, and the hurt in the mouth may also look like in their form oral candidiasis. The loss of appetite, weight loss of abdominal pain, cramps and inflammation in the intestinal wall can affect the status of appetite, digestion and food absorption. Characteristics and a little inflammation arising from Crohn’s disease can be transmitted by the intestinal wall in other internal organs, such as: the bladder or cervix, and they are linked to each other, and this compound is called a fistula, it can also lead to the formation of abscess, which is a swollen wound full of pus (PUs). Fisheries are especially distributed in the anal opening area, and the perineum phistel is called perineum fistula. Other symptoms with Crohn’s disease may suffer from an advanced degree of symptoms: Fever. Fatigue. arthritis. Ophthalmia. Skin problems. Inflammation of the liver or in bile ducts. Delayed growth and obstacles in sexual development in infected children. The path of Crohn’s disease varies from person to person, and there may be long periods free from any symptoms, or other regular periods of abdominal pain and diarrhea that are sometimes accompanied by fever or bleeding. Causes and factors of the risk of Crohn’s disease There is no clear cause of revival of inflammation within the framework of Crohn’s disease, and researchers are not sure that psychological pressure or nutrition is the two most important officials, although both causes can increase the symptoms of Crohn’s disease. The causes of Crohn’s disease in the following are the most important expected causes of Crohn’s disease: The reactions of the immune system are very likely that a specific virus or bacterium is the cause of Crohn’s disease. The primary caused by the disease is a mecobacterium sub -species paratuberculosis – MAP, a type of germs that mainly cause bowel diseases in cows. The researchers found that this bacterium is worn in the blood of the majority of people with Crohn’s disease as it is present in people with Ulcent Colitis, but there is no conclusive evidence that this bacterium is the cause of Crohn’s disease, and some researchers believe that a certain genetic defect provides an abnormal reaction to the bacteria. The majority of researchers believe that people with Crohn’s disease are infected with it due to the wrong response issued by their immune system for a specific type of germs permanently in the intestines. Genetic causes have about 20% of people with Crohn’s disease also parents, fraternity or children with Crohn’s disease, and a mutation mutation was found in the gene named NOD2 / Card15 in the majority of the injured, which is the factor responsible for the occurrence of primary symptoms at an early age, in addition to a high possibility to resolve the disease. The genetic that occurs and which is likely to be responsible for the rise of Crohn’s disease. Factors increase the risk of Crohn’s disease of Crohn’s disease affecting men and women, and risk factors include: The age of Crohn’s disease can occur at different ages, but it is likely that the incidence of primary symptoms at an early age, and most patients in the age phase are diagnosed between 20-30 years. The ethnic origin, although people of white origin are most likely to develop Crohn’s disease, but Crohn’s disease can also occur in other ethnic groups. Family history risk to develop Crohn’s disease is greater in people who have a first degree near Crohn’s disease, as the brother with Crohn’s disease increases the risk of 30 times infection. The place of housing for a long time in a civilian area, or near an industrial area that increases the risk of Crohn’s disease, and as this disease is more common among the population of major cities and industrial areas, this may be an indication that the environmental factor is one of the factors that cause Crohn’s disease. People living in the northern half of the world are more likely to develop Crohn’s disease than other areas. Food rich in fats, or food foods, can be an extra effective factor. Smoking smoking is more likely to develop a non -smoker Crohn disease, and treatments in smokers are less effective and can aggravate Crohn’s disease. Medicine Although its effects have not been completely proven, research recognizes a relationship between taking isotretinoin and the rise of a for ulcerative bowel infections. Complications of Crohn’s disease can lead to the occurrence of many complications that include: bowel obstruction. Upload. Family. Malnutrition due to internal fistulas. Inflammation of external crops and an abscess. Longbow cancer, but it is often rare. The diagnosis of Crohn’s disease is diagnosed with the following: x Ray: Where the end of the small intestine looks narrow and ugly, and sometimes a fistula can also appear. Colonoscopy: Divorced ulcers, wounds note is not order, and a distinctive injury at the end -minimum bowel. Take samples of the affected tissues for microscopic examination: through which the acute and chronic inflammatory filtrase can be seen and contains giant cells that characterize the disease. Crohn’s disease treatment is done using one of the following means: 1. AminosaliLate of the follower of the following when the Crohn disease is still in a light and even medium degree, and it is taken orally with a dose of 4 grams per day, and if the patient’s body responds well, you must continue to treat the situation (maintenance treatment). If this treatment fails, it should be transferred to steroids immediately. 2. Sydroid therapy is treated with oral steroids, or intravenously depending on the severity of the disease, and in light of the numerous side effects of prednisolon and other steroids it is still constantly developing steroid with lower side effects. Bodesonide is a system (synthetic). It has been found that 9 milligrams of podzonide per day, and Bridnisolone 40 milligrams per day equals the treatment of Crohn’s disease, but with lower side effects. When steroids do not treat the disease of Crohn, or when the patient’s stage begins to attach, the treatment with equivalent medicine for immune efficiency, such as: azathioprine, and the rate of induction of the rection are about 75%within 3 months. In addition to its success in the initial treatment, the medicine also remains effective in reducing the dose of steroids, and it is also effective in closing fistulas and maintaining the gift of the disease. 3. Antibiotics have proof that the antibiotic effect and effectiveness of antibiotics in the treatment of Crohn’s disease without a doubt. Metronidazole has been effectively proven in the treatment of injuries around the anal opening in Crohn’s disease in the major intestines and maintaining surgery. The dose used from it is 20 milligrams/ kilograms per day, this quantity is unlikely among quite a few people with nausea and metallic taste in the mouth, making it difficult to treat this medicine. Ciprofloxacin is also effective if the disease is active in the treatment of wounds around the anal opening. 4. Other medications are the most experiments that are looking for the effects and effectiveness of new medicines that control the immune system, have been performed and tested on Crohn’s disease, these experiments in which medication has been tested, which contain protective inflammation rate. The anti -tumor is the anti -tumor factor, which has biological effects that can have the greatest importance in the production of inflammory. Double blinds and supervisory experiences indicate the effectiveness of monoism for a tumor -necked agent once and intravenously in a dose of 5 milligrams/ kilograms, or by giving 3 injections within a few weeks, and the treatment can be achieved in people with Crohn’s disease resistant treatment with steroids. Prevention of Crohn’s disease There is no way to prevent Crohn’s disease, but there are some ways to reduce the appearance of symptoms, such as eating healthy foods and avoiding food rich in fat. Stop smoking. In fact, alternative treatments cannot be treated with herbs with herbs, but the following herbs can help relieve symptoms: turmeric. Chamomile. Wood plant. Aloe Vera.