A study that connects the accumulation of fat in the abdomen and an increased risk of psoriasis

A recent study revealed that the accumulation of fat in the abdominal area is more associated with an increase in the risk of psoriasis, compared to total body fat, especially in women. The study published in the Journal of Investigative Dermatology (JID) showed that ‘central obesity’, which is the increase in fat in the abdominal area, contributes to increasing the risk of psoriasis, regardless of genetic predisposition. Psoriasis is a skin disease that causes a rash and crusts that occur on the knees, elbows, body stem and scalp and itching regularly. Although the relationship between increased general fat and the risk of psoriasis is known, the effect of spreading fats on the body and genetic willingness is still sufficiently clear. In the study, the researchers relied on the data of more than 330,000 people with white British assets in the British BioBank database in the UK, including more than 9,000 people with psoriasis. The researchers used 25 different indicators to spread body fat, using traditional means and advanced image techniques, to measure the extent of their connection to psoriasis. The accumulated fat in the waist area, the most important researcher for the study, said Ravi Ramisor: “The results of our study show that the place of storage in the body is of great importance when it comes to the risk of psoriasis.” “The accumulated fat in the waist area plays an important role in particular. This is why important implications for identifying individuals who are most vulnerable to psoriasis or who can suffer from a more serious illness, as well as how we are dealing with prevention and treatment.” Catherine Smith said: “In light of the high obesity rate worldwide, the importance of understanding the effect of the patterns of fat distribution in the body on chronic inflammatory diseases such as psoriasis.” She added: “The results of the study indicate that abdominal fat contributes to increasing the risk of psoriasis, regardless of genetic propensity, which increases the importance of measuring the middle circumference and applies proactive strategies to maintain healthy weight within the care of psoriasis patients.” Since this study only included individuals of white British descent, the possibility of spreading these results on more diverse population groups may be limited, and it is recommended to conduct future studies dependent on the confirmed diagnoses of dermatologists and a greater ethnic diversity; To verify more than the validity of these results and develop risk classification instruments more accurately. “We were amazed at the strength of the connection between the different indicators of the stomach fat and the risk of psoriasis, especially in women. This relationship indicates that there may be inherent biological mechanisms that contribute to the disease that is not fully understood and earn more research.” The results of this study can contribute to improving early prediction mechanisms of psoriasis and the guidance of personal protection strategies.