Bubbly disease: symptoms, causes and treatment

Pemphigus bubble with bubble sponsorship is a dangerous chronic disease that occurs as blisters in the skin and mucous membranes, as the immune system in the healthy natural condition produces antibodies against germs and viruses that attack the body, and in the case of the bubble, the body accidentally produces antibodies against the skin itself. The specific proteins in the skin cells targeted by this self -antibodys are called Desmogleins, which form glue that connects adjacent cells with each other in the upper skin layer. In the development of bubbles, the cells are separated into a process called acantholysis. The forms of bubbles, the two essential images of the bubble, are: Pemphigus vulgaris, and Pemphigus foliaceous, in the following more details: 1. The stationery in this type of disease develops patients in the superficial skin, but there are no injuries in the mucosa. 2. The common bubble in this type of disease is deeper into the outer layer of the skin, as this type of disease begins with stomachs in the mucous membrane in the mouth and only later the skin signs arise. Other mucous membranes, such as those in sexual organs, conjunctiva and esophagus, may also be in this kind. The connection between the bubble and a number of malignant diseases is very complicated, as there is a single type of bubble called, called paraneoplastic pemphigus for this type of clinical and laboratory functions, and is characterized by the large association with the mouth and lips. Symptoms of bubble disease that are in the bubble bubble, soft, soft, full of fluid and easily exploded with the formation of painful ulcers that can sometimes become inflamed. Causes and factors of the risk of bubble diseases include the causes of infection as follows: 1. Genetic factors, the most important of which is the complex of the great historical National Patubility complex in humans, where the complex particles of the great histological compatibility are located on the covers of the cells of the immune system. 2. Ecosonce of reports that environmental factors contribute to the rise and development of bubble disease, and include: medication. Food products. Insecticides. Special materials for gardening. Sunlight. X -ray. Inflammatory factors. Pregnancy. Malignant diseases. Psychological pressure. 3.. Medicine with a specific chemical composition. This medication is a key factor that contributes to the formation and development of bubble diseases. Among these drugs: Penicillalamine. Captopril. Medicine to treat high blood pressure (calcium channels). Penicillins. Anti -pain medicine of different types. 4. Other factors may play some other factors in the formation of pemfigation, such as: food products with a chemical composition similar to the composition of some medications prescribed above. Inflammatory factors, such as: herpes family viruses and bacteria from different families. Bubble disease complications include complications as follows: infection that spreads in the bloodstream. malnutrition; Because painful mouthwees make it difficult to eat. The side effects of the medicine, such as: high blood pressure and infection. Diagnosis of bubble disease becomes clinical and determines according to various tests, including: the date of the disease. Physical examination of the skin and mucous membranes. The results of the biopathic examination taken from the injured skin in which cell separation can appear. Immunofluorescept -test to detect the presence of self -antibodies in the skin and blood. There are many additional tests to accurately identify opposites in some laboratories. The treatment of bubble diseases The treatment of bubbles aims to prevent exposure to potential external factors that exacerbate the disease and impede the production of harmful antibodies. There is a need to protect open and secretory areas as well as antibiotics to treat secondary inflammation with the conditions that have exploded. Medicines are performed by taking steroids in high doses that include predisone, which is most effective, and if the disease is controlled, steroid doses are gradually reduced, as there are sometimes a specific dose of steroids to control the disease. There are many immune brakes aimed at reducing the required dose of steroids, such as: azathioprine. Methotrexate. Cyclophosphamide. Mycophenolat. Mofetil. It should be noted that this strong medicine in itself has very difficult side effects, and sometimes the treatment of immunological proteins is directly given (iviglobulin – ivig), and the extent of the treatment is measured by the extent to which the rise of new provisions and the beginning of the construction of new skin in the areas that exploded.