A German research team develops a vaccine against Corona via the nose

A German research team has managed to develop a new vaccine against the Corona virus, which can “be given by the nose.” The new vaccine belongs to the ‘talented vaccines’, which is prepared using a bacterium or virus, but adapted to be less effective. This vaccine can help prevent the infection better than the injected vaccines in the muscles, according to what was mentioned in the magazine “Nature .. Microbiology”. And in that kind of vaccine; The weak pathogen can multiply within the body, but it cannot cause the disease because it is adjusted so that it becomes less fierce. ‘Live Vaccines’ works by motivating the immune system to deliver a preventative reaction against the pathogen. And because the vaccine contains a weak form of the nurse, the immune system can identify it as a stranger and thus respond to it, without causing a serious illness. This vaccine can lead to a long -term immunity to the disease. Two types of vaccine and corona viruses are mainly distributed by air; When the injured speak, cough, sneeze or laugh, they expel drops of saliva containing the virus. Other people catch air pathogens, and they develop infection. The German research team targeted the fight against the Corona virus, where it is first,; That is, in the mucous membranes of the nose, mouth and throat. In the fall of last year, two types of vaccinations were approved by nose sprays in India and China, but the producers of the developed nose virus in India and China did not apply after asking for approval in Europe. Other nasal vaccines are currently undergoing development and testing around the world, and the benefits of the Rhinus vaccine can exceed an alternative to people who are afraid of needles. When the vaccine is injected into the muscles, immunity is mainly penetrated into the blood and throughout the body. But that means that the immune system will not discover or fight Corona viruses, except relatively late in the infection, when viruses enter blood through the mucous membranes into the upper respiratory system. Therefore; According to the German -Jacob TremBRT researcher at the Institute for Viruses at the University of Frex, the world must “intercept the Corona virus in the respiratory system early.” And the Rhinus vaccines are more effective in this regard of the inaccurate, an injected vaccines, which fails or struggles to reach the place through which the virus enters the first, which is the mucous membranes. The perfect scenario in the perfect scenario, the vibrant vaccine in the nose stimulates the composition of the “immunoglobulin” (a type of protein produced by the immune system to combat diseases) for the anti -body directly at the place of the injury, which occurs the incidence of infection in the first place. The most common immunoglobin in the mucous membranes of the airways is capable of neutralizing pathogens by connecting them and preventing them from infecting the respiratory cells. Meanwhile, the vaccine stimulates ‘systemic immune response’ (responding by the immune system), which helps provide effective comprehensive protection against infection. “The TV cells in the lung tissue play a useful role similar to the antibodies in the mucosa,” says the specialist in lung and respiratory diseases, Geralddine Naayels, noting that “white blood cells in the affected tissues remain long after the infection, and remember the causes of the pathogens they had before.” Thanks to the presence of a part of these cells, which are motivated by the nasal vaccine in the lungs, they can respond quickly to the viruses entering the airways. Rodents are currently the most important genetically modified living organisms to look for the new Corona virus as they can develop the same virus variables, such as humans, and develop similar symptoms. Stopping proliferation and the researchers found that the virus after two doses of vaccine could no longer multiply in these organisms, and scientists also insulted the effectiveness of the live vaccine with the efficiency of vaccines injected into the muscles. The performance of the ‘Live Liven’ was better than other vaccines in all standards, and this may be due to the fact that the vaccine given by the nose builds immunity directly on the virus importing. In addition, the vibrant vaccine contains all components of the virus, not just the spike protein, as in other vaccines. Although this protein is already the most important antigen of the virus, the immune system can also recognize the virus of about 20 other protein. The best protection against the new Corona virus was provided by the double vaccination of the nose, followed by the combination of muscle injection with a vaccine currently used, and the subsequent nose that gives the abusive live vaccine. This means that the vibrant vaccine can be particularly interesting as improved. The researchers say the next step is the safety test, given the possibility of giving it in the form of sprays or nasal drops. This vaccine is a good option for use in areas that are difficult to reach medical teams as it is not expensive in production, and easy to store and transport. Also read: