A team of researchers from Britain and India revealed an unexpected mechanism that helps the body cells accelerate wound healing. According to the study published in the specialized magazine “Nature Cell”, the cells change their shapes according to the curves of the gaps that try to close it, which increases their ability to fasten the affected tissues. The results indicate that the endoplasmic reticulum in the cells plays an important role in determining the way the cells move to close cracks and gaps. This network is an essential ‘organ’. This network is divided into two types, the first is ‘rough’ and is covered with ribosomes and is responsible for the production of proteins directed from the cell or to its membranes, and the second is ‘smooth’ and does not have ribosomes, but it plays important roles in the production of fats and hormones, stores potassium ions and helps remove the toxins. Thanks to these various important functions, the endoplasmic network is an important than in cell life and activity. This discovery acquires special interest, given that ‘epithelial cells’, which cover the internal and external surfaces of the body, are the first line of defense against injury, infection and fluid loss, in addition to their role in absorbing nutrients, waste and enzyme production and hormones. Advanced techniques The results of the study showed that epithelial cells did not move randomly to close wounds, but rather to reorganize their internal structure according to the form of the gap. If the edges are convex, the endoplasmic network within the cell becomes accurate tubes, and the cells depend on the ‘wide crawling’ style by expanding flat ends that push them to the gap to close it. As far as the concave edges are concerned, the endoplasmic network takes a flat shape in the form of plates, and the cells use a movement similar to the ‘stretch of the thread’ while contracting to extract and collect the edges. Scientists suggest this behavior that the driving forces in convex turns, and the attractive forces in concave turns change the form of the endoplasmic network, thus accurately define the movement mechanism followed by cells. This discovery is not limited to an important scientific step, but can change the rules of the game in the field of medicine, the participating researcher, Keshavanaraana, the research team used advanced techniques to create accurate gaps in the cell layers, and then used them to high -resolution portrayal, and sports models to understand the structure of the endoplasmic network and to terminate this cellos. Simran Rawwal, the lead author of the study of the “Tata Basic Research Institute” in Hyderabad, India, who took over most of the experiments, said that wound healing is a basic response to the injury, and emphasizes that “our study opens new horizons to understand the mechanisms of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of the network of Co -researcher Baradib Kishvanaraana, who developed the sports model during his work at the University of Berlingham, Britain, believes that this discovery is not only an important scientific step, but that it is a ‘qualitative shift’. He emphasized that the realization of the important role of the endoplasmic network in cell movement may be the way to develop more effective treatments for wounds, create new ways to renew the damaged tissues, and perhaps develop better strategies to reduce the spread of cancer cells or to slow down the metastasis. This discovery is an important addition to the field of cell biology, as the understanding of the movement of cells and wound healing mechanisms remains an important field of research, which has direct effects on the development of modern treatments, whether within the framework of renewal medicine or in the face of chronic diseases such as cancer.
Discover a new cell mechanism that accelerates wound healing
