Researchers discover 'universal' genetic factors that cause depression

One of the largest and most diverse genetic studies in the world has ever revealed almost 300 genetic ties for depression ‘previously unknown’. The researchers knew the new genetic risk factors for depression around the world’s largest population for the first time, enabling the risk of depression, regardless of sweating. The study published in the ‘Cell’ Journal (Cell) found that 100 new -found genetic differences – a group of small differences in the DNA order that were identified as a result of the inclusion of people of Africa, East Asian, Spanish and Asian. Previous research on genetics for depression focused mainly on the white population, originally from people living in Europe. Therefore, treatments developed using genetic methods may not be effective in other breeds, leading to the expansion of the already existing healthy inequality gap. It is known that each genetic variable has a very small effect on the total risk of depression, and if someone has multiple variables, these small effects can accumulate, increasing the risk of infection. Good results allow the research team to predict more precisely the risk of an individual’s depression by observing the newly identified variables. An international team of scientists, led by the University of Edinburgh and Kings London College, studied unidentified genetic data for more than 5 million people in 29 countries around the world; 1 out of 4 individuals who were included in the study of non -European origin. The researchers identified a total of 700 differences in the genetic code of individuals associated with the development of depression, and almost half of them were not previously associated with this condition, indicating the cause of 308 specific genes in this condition. The genetic variables specified with neurons are also linked across different parts of the brain, including areas that control passion. The researchers pointed out that the results provide a new insight into the effect of depression on the brain, and that they provide possible new treatment targets. The author, Andrew McKentech, said that there are great gaps in our understanding of clinical depression, which limit the chances of improving the results for the people involved. Macintosh added that the largest and most representative studies in the world are needed to provide the necessary visions to develop new and better treatments, and to prevent the disease in people who are more common in this condition.