The success of the pressure of "Benkriasia Islands" .. a possible transformation in the treatment of diabetes

An international team of scientists has announced their success with the pressure of a functional human “Benkriyas Islands” using 3D printing technology, which paves the way for revolutionary treatment for type 1 diabetes -patients. The first type of diabetes is a chronic disease of auto -immune diseases, as the body’s immune system attacks and destroys the cells that are insulin known as ‘roots’ in the pancreas; As a result, the body cannot produce insulin needed to regulate blood sugar levels. Type 1 diabetic depends on daily insulin injections due to the destruction of the immune system of the benchmarks responsible for the production of this hormone, and scientists sought years ago to replace these islands by planting, but they faced major challenges associated with cell loss, and the difficulty. According to the study published during the activities of the European Association for Organ Transplant; The use of scientists is a new ‘biological ink’ consisting of ‘Allathians’, which is a natural substance extracted from algae, along with a nisal cell tissue. This mixture has enabled the team to push a high -density “Benkriya Islands” and can remain alive and active for up to three weeks, and the ability to respond to sugar and maintain insulin effectively. Contrary to traditional implants that occur in the liver and often result in a large percentage of cultivated cells; The printed roots are designed to be planted under the skin, which is a simple process that requires only a local anesthesia and a small slit, and according to the team, this ‘less tested’ approach can provide a safer and comfortable option for patients. The team created the natural pancreas environment again so that the cultivated cells can survive and work better, using biological ink that mimics the supporting structure of the pancreas, oxygen and the necessary nutrients. To protect fragile cells during printing, the team developed a more friendly way by reducing the used pressure and reducing pressure of printing, and this modification helped reduce mechanical tension and retain the natural form of the islands, which is an important technical challenge that has always hampered the progress of biological printing. A possible transformation in the treatment of diabetes and experiments showed that more than 90% of cells after printing remained alive, as it showed a better response to glucose levels compared to traditional methods, which meant more accurate secretion of insulin, and after 21 days, this islands maintained their structure without a block or collapse. The printed structures were characterized by a porous design that easily enables oxygen flow and nutrients in the cells, which helps to improve their health, and to support the formation of the blood vessels needed to survive after the transplant. The researchers believe that this design is a key to improving root performance after being planted in the body, and emphasizes that the present study is one of the first studies to use real human islands instead of animal cells that show many encouraging results, and as they say they approach the possibility of producing a ready -made treatment that can be used without the need for frequent insulin. The team is currently working to test the roots printed in animal models, as well as to investigate freezing techniques that allow these structures to store and spread it worldwide. It is also underway to use alternative sources of cells, such as roots derived from stem cells or even cells of pigs, in a move aimed at overcoming the lack of donors. Although treatment is still in its experimental stages, scientists see a major turning point in the field of diabetes treatment; If clinical experiences prove its effectiveness, this innovation can change the lives of millions of injured people around the world.