Secret for longevity unlock? Naked Mole Rat's DNA Report Mechanism offers promising lifetime clues

A new study examining the extraordinary life of the naked mole gear has identified a developed DNA recovery mechanism that is unique to the species. These bizarre rodents with a excavator boast a maximum life of almost 40 years, making them the world’s longest lively rodent known to science. The findings, recently published in the journal Science, provide possible insights to why naked moles show remarkable resistance to a wide range of age -related diseases. The animals are naturally immune to cancer, show no measurable deterioration of the brain and spinal cord, and are resistant to arthritis. This unique resilience made them a topic of intense scientific investigation. The research, led by a team from Tonji University in Shanghai, China, focused specifically on the natural process of DNA recovery within the cells of the body. If genetic material is damaged, an undamaged DNA string is typically used as a template to solve the fraction. The study determined a specific protein involved in the Mol-gear’s damage sensation and recovery system, suggesting that this highly effective recovery is the cause of their extensive, disease-free lives. Professor Gabriel Balmus, who comments on the breakthrough, commenting on the breakthrough, who studies DNA recovery and aging at the University of Cambridge, described the discovery as exciting and simply ‘the tip of the iceberg’ to fully understand the animals’ extraordinary long lives. “You can think of CGAs as a biological lego piece-the-same basic form in people and naked moles, but in the mole gear version, a few connections are turned around, making it compose a very different structure and function,” Balmus said. He explained that more millions of years of evolution, mere mole rats have “re -wired” this cellular track and “used it to their advantage”. “This finding raises fundamental questions: How did evolution reprogram the same protein to act in reverse? What has changed? And is it an isolated case or part of a broader evolutionary pattern?” “I think if we could reverse the biology of the naked mole gear,” says Prof Balmus, “we can bring some much-needed therapies to an outdated society.”