Dangerous lip injuries ... a new treatment method

Scientists have developed a three -dimensional model of lip cells using modern techniques, enabling the ability to develop new treatments for serious lip injuries, according to a study published by the boundaries. The researchers were able to “immortalize” the lip cells taken from donors, through which these cells can be used as laboratory models, injuries, infection that affects, studies and tests new treatments. Making lip cells means to adapt it genetically to be able to divide and reproduce almost endlessly in a laboratory environment, instead of stopping reproduction, and dying after a limited number of sections, as is the case in normal cells. The mixing of lip cells The natural cells usually contain an internal system that controls their life cycle, and stops their reproduction after a certain period, but the “immortalization” process includes disruption of this system, so that the cells continue to divide without stopping. The lips are an important part of the face, not just about beauty; It contributes to many basic activities such as speech, eating and drinking. According to the author’s co -author, Martin Degen, a researcher at Bern University, it may be difficult to restore lip injuries due to the complexity of the lipstick. Digen says the lips are a prominent feature of the face, but there were no laboratory models based on lipsticks to help scientists develop suitable treatments for these injuries. The treatment of severe lip injuries and the primary cells, taken directly from donors, is the perfect choice for research because it has similar properties of the original material. But these cells cannot be reproduced indefinitely, in addition to the fact that it is rare and difficult to achieve, and to overcome these challenges that have the work of the research team to “immortalize” lip cells so that it can be used for long periods. Scientists have collected skin cells from two patients: one of them suffers from a lip tap, and the other is subject to the treatment of the bunny lip, and the cells are genetically modified using a technique that relies on a ‘reactionary carrier’, to change the gene responsible for stopping the cell life cycle, as well as changing the length of telomosa. The modified cells of a series of tests were undergone to ensure their genetic stability, and they were tested to verify that they did not obtain cancerous properties, and these tests included the search for any chromosome disorders, and the cultivation of cells on a soft medium that grown only cancer cells. Promising results and challenges. The results showed that there are no chromosome abnormalities, and the cells could not grow on the soft medium, indicating their safety, and scientists also emphasized that these modified cells act similar to the original cells when the production of protein and ribosia DNA is tested. The scientists tested the possibility of using these cells as models to study the healing of wounds and infection, and a sample cells were scratched to study the healing ability. The uneducated cells showed their ability to close the wound within eight hours, while the cells were treated faster with wound growth factors, corresponding to the results of restoring skin cells in other parts of the body. Scientists have also developed a three -dimensional model of cells, and they have hit him with the fungus of Candida Albicans, a yeast that can cause serious infections in people with a weak immunity, or those with lip. The affected cells showed a natural reaction as the nurseries entered the fabric as if it were already lip tissue, which proved the effectiveness of the model. ‘Digen’ explains that the understanding of the genetic and cellular traces associated with the slit of the lip and the roof of the throat, through the use of 3D models for healthy lip cells, provides great abilities for application in many other medical fields. The researchers say that the biggest challenge is the variety of the types of lipstick that may be superficial or mucus, which according to research question may require a certain type of cells, but he indicated that his team has “the tools needed to determine or purify these different cells within the laboratory.”