Thalassemia -disease: symptoms, causes and treatment

Thalassemia, sponsored by Thalassemia, is a genetic disorder in the blood, that is, it is transmitted from parents to children by genes and occurs when the body does not produce enough protein called hemoglobin, which is an important part of red blood cells, when there is not enough hemoglobin; So there are fewer healthy red blood cells that are transmitted in the bloodstream. Red blood cells transport oxygen to all the cells of the body, oxygen is the fuel that the cells use to work, and if there is not enough healthy red blood cells, a sufficient amount of oxygen is also not linked to all other body cells, which can cause a person to feel tired, weak or short of breath. It is a condition called anemia where people with oceania can suffer from a mild or severe anemia, and severe anemia can damage the organs and lead to death. A pregnant woman with talassemia is obtained by immunity to malaria, and the possibilities of survival of malaria rise in areas known as the spread of malaria. For this reason, this disease is widespread in tropical areas and the areas nearby. Symptoms of thalassemia There are different types of thalassemia, where the signs and symptoms you suffer from depend on the type and intensity of your condition, and the signs and symptoms of thalassemia may include: fatigue. Weakness. Forex or yellowish skin. Facial leg distortions. Slow growth. Flatulence. Dark urine. Some children show signs and symptoms of thalassemia at birth where others develop it during the first two years of life, and some people who have one infected hemoglobin gene that do not show symptoms of thalassemia. The causes and factors of the risk of talassemia include the most important causes and factors of the risk of ice. For example, if both parents have a flawed gene that causes the great beta -thal assemia, then there is one in every 4 that each child is born in this state, as the parents of the child with Oceania are usually transported to snowmille, and that means they have only one of the flawed genes. 2. The risk of ice infection includes factors that increase the risk of snowmaker. Sweet: Thrilloria often occurs with African Americans and with people from the Mediterranean and Southeast Asia. The complications of thalassemia include complications as follows: 1. The medium complications of snowmie include possible complications from medium to severe thalassemia disease. For hormones that regulate operation throughout the body. Snowmy infection infections suffer from an increased risk of infection, and this is especially true if you have undergone a spleen removal. 2. Serious complications of snowmy in severe thalassemia cases may prevent the following complications: Bone disorders can lead to dependence on the extension of the bone marrow, resulting in the width of your legs, as it can lead to an abnormal bone structure, especially in your face and skull, and the extension of bone marrow can also make the bones thin and brush; This increases the chance to break the legs. Valley enlargement helps your body fight infection and filter unwanted substances, such as: old or damaged blood cells, where thalassemia is often accompanied by the destruction of a large number of red blood cells, and this results in enlarged spleen and works with greater effort than usual. An enlarged spleen can aggravate anemia, and it can reduce the age of red blood cells, so if the spleen grows very significantly, your doctor may suggest an operation to remove it. The inertia of the growth rate can slow down the growth of the child and slow down puberty. Heart problems can be accompanied by congestive heart failure and heart rhythm deviation with severe thalassemia. Diagnosis of thalassemia In most cases, alpha -thalassemia is diagnosed with a newborn examination, which is a blood test given for the first time at the birth of the child, as children with great snowmaking, symptoms of anemia or growth. If the doctor suspects the Alpha -Thadisa, he will take a blood sample for the test where blood tests can reveal the presence of lights and diverse red blood cells in shape and size or smaller than normal, they can also discover the low number of red blood cells and cells with an unequal distribution of hemoglobin, which makes them look like a bull eye when it sees. Blood tests can also measure the amount of iron in the blood, assessment of hemoglobin and the child’s DNA testing in search of abnormal hemoglobin genes, where both parents are pregnant with the disturbance of the alpha -tha, doctors can perform tests on the fetus before the birth, and this is done by a sample of the placent: in the placent that occurs around 11 weeks of pregnancy. the test. Extinguish: which is usually performed after about 16 weeks of pregnancy and contains the removal of a sample of the fluid around the fetus. Thalassemia therapy does not need light forms of thalassemia to treat, but for medium snowmia, treatments may include: 1. Blood transfusion often requires the most serious forms of thalassemia that regularly blood transfusion processes, perhaps every few weeks, and over time blood violates blood, which can lead to heart, liver and other organs. 2.. This treatment therapy is a treatment for removing excess iron from the blood as iron may accumulate due to regular blood transfusion, and some people with oceania who do not undergo blood transfusion may also be driven by oil. To get rid of your body from excess iron, you may need to take an oral medicine, such as: deferasirox, deferiprons or deferoxamine, which is given by the needle. 3. System transplantation can be stem cell transplantation, which is also called in some cases a bone marrow transplant. If children with severe Oceania can eliminate the need for lifelong blood transfusions and medication to control excess iron. This procedure includes receiving groups of stem cells from a compatible donor and usually the brother. Prevention of thalassemia In most cases you cannot prevent thalassemia, if you have snowmia, or if you wear a gene of thalassemia, you should talk to a genetic consultant to obtain instructions if you want children. There is a form of diagnostic using the birth technique, which examines the fetus in the early stages in search of genetic mutations related to fertilizer in the laboratory. The procedure includes the recycling of ripe eggs and fertilizer of sperm in a plate in the laboratory, then the embryos are tested in search of poor genes, and only embryos that do not have genetic defects in the uterus are implanted. Common species consist of hemoglobin of two types of protein: alpha -gloin and beta -gloin, where thalassemia occurs when there is a defect in a gene that helps control the production of one of these protein. There are two main types of thalassemia: 1. Alpha -thalassemia occurs when the gene or genes associated with alpha glue protein are between missing or changing, most often affects a toesemia, people from Southeast Asia, the Middle East, China and African aftermath. 2. .to Beta when similar genetic defects affect the production of beta globin protein found in beta, and which often occurs in Chinese, other Asians and African Americans. There are many forms of thalassemia and each type has many different subspecies, as it includes both the alpha and beta. The genetic imbalance should be inherited from both parents to develop great thalassemia disease, while younger thalassemia disease occurs when you receive the lack of none of the parents, because people with this type of disorder are the carriers of the disease and often do not show symptoms.