"A distance of tension" .. a new hope for the treatment of colon and rectal cancer

A new research has revealed how to disrupt chronic tension, the balance of intestinal microbes and the progress of colon and rectal cancer, and the results of the study open new horizons to preventing and treating disease. The study, which was revealed during the activities of the United States for digestive diseases, reads; This year in Austria, the tension eliminates some gut bacteria, which helps with the development of colon and rectum cancer. Chronic tension causes disorders of the body’s function, including chronic inflammation that can negatively affect the health of the intestines, and it can affect the immune system, which can make it less able to fight cancer cells, as well as tension increases hormones such as cortisol, which impede the immune responses and contribute to the dissolution of inflammation. The bacteria play an important role in the health of the digestive system and immunity; A healthy balance between microbes protects from infections and increases immunity, and the disorder increases the possibility of chronic intestinal inflammation, which is associated with the development of colon cancer, and the researchers have identified a specific bacterial type as a potential therapeutic target for patients with colon and rectum cancer. The researchers used a mixture of 4 different antibiotics (Vancouveromcin, ambitions, nucleben and metronidazole); To eliminate all or most intestinal microbes in experimental mice with the aim of “cleaning” the digestive microbes completely, researchers in this way can study the effect of the absence of these microbes on the development of colon and rectal cancer. After eliminating the intestinal microbes using antibiotics, the researchers transplanted a visible microbial agent, a procedure in which microbes from a person or a healthy animal were transferred to the bowel’s intestines; To verify whether intestinal microbes are needed to accelerate the development of colon and rectal cancer when exposed to chronic stress. Colon and rectal cancer The results showed that chronic stress not only increased the growth of the crop, but also reduced the beneficial gut bacteria, especially the gender of lactopasilus, which is needed for a healthy immune response to cancer. The researchers note that the development of colon and rectal cancer associated with stress can be attributed to a decrease in useful gut bacteria as it weakens the body’s immune response to cancer. Locopasylus, which is characterized by the sensitivity to the Vanquicin and the Ambestin, is exhausted by antibiotic cocktails in both control and stress groups, and it emphasizes its decisive role in maintaining the health of the intestines, and the potential connection with the development of colon and rectal cancer under chronic pressure. And to investigate how lactopasilus affects the levels of TD cells of the type of CD8+, which plays a decisive role in the immunity of the anti -tumor, and the development of colon and rectal cancer; The researchers gave mice supplements from Lactopasilus during chronic tension, and they noticed low tumor formation. Through faeces analysis, the researchers found that gut bacteria of the type of lactopasilus especially organize the metabolism of bile acids and improve the function of the CD8+T cells, indicating how the lactopasilus can improve the anti -tumor immunity. Anti -Tumor medication and the study revealed another surprise; The researchers say that they initially considered that the Lactopasilus bacteria can improve the function of the anti -tumor immunity in T -cells CD8+ by stimulating the production of metabolic substances, but laboratory experiments have shown that these bacteria cannot stimulate the production of certain materials in the TT8+. of certain materials cannot stimulate intestine environment to activate these immune functions. The researchers believe that these results are a new step towards a deeper understanding of the role that beneficial microbes play in the fight against cancer, especially in patients with chronic stress. The study also indicates that the combination of traditional anti -tumors and beneficial gut bacterial supplements may be an appropriate therapeutic strategy for colon and rectal cancer patients associated with stress. Colon and rectal cancer is a major health problem around the world as it is classified as one of the most common types of cancer, and this is a major cause of cancer-related deaths, and expectations indicate that the infection rate will see in the next decade due to several factors, such as age, unhealthy diet, lack of physical activity and obesity. The research team intends to collect stools and crops from colon and rectal cancer patients, to analyze changes in intestinal microbes from individuals suffering from chronic stress, and who do not suffer from it. This study sheds light on the complicated relationship between chronic tension, intestinal microbes, colon and rectal cancer, and confirms that strategies for the recovery of bowel health can play a decisive role in caring for cancer patients, especially those suffering from chronic stress.