The discovery of sperm installation paves the way to diagnose the causes of infertility

Researchers from Japan have discovered that two specific proteins are CFAP91 and EFCAB5, which play an important role in sperm movement, and that the loss of the function of one of them significantly reduces the fertility. The results of the study, published by the “Nature Communications” patrol, said that the CFAP91 protein is found in the composition of the tail of the sperm, called the ‘sweep’ and is responsible to push the sperm forward until it reaches the egg. But the whip is not just a simple thread, but rather a complex building that includes ‘radiological thorns’; These thorns serve as accurate columns that organize the movement of the whip and ensure that the strikes it performed are consistent and strong. The researchers at the University of Osaka said that CFAP91 is considered one of the most important components of these thorns, that is, it is an important piece in the structure that controls the movement of the sperm. If this protein is absent or disrupted, this organization collapses, the sperm fails in the natural movement, and becomes unable to reach the egg; Therefore, the absence of CFAP91 is directly associated with poor fertility or infertility in men. Regarding the EFCAB5 protein, it works near the CFAP91 protein, as if it were an assistant for it, and the scientists say that its role is not to build the whip itself, but rather to control the exact sperm movement, such as how the whip can see the sweep and the severity of the sweep, and it can be considered as a “wave” or ” Injuriability – The World Health Organization affects millions of people – and leaves an impact on their families and local societies, and it is estimated that almost one person in every 6 children of the loving age is infertility around the world. The male reproductive system is often infected due to problems in the ejaculating semen, numbness of sperm, low production levels or their distortion. The female reproductive system can develop infertility due to a group of abnormalities attached to the ovaries, uterus, fallopian tubes and the endocrine system. Infertility can be primary or secondary, and the initial infertility is that a person is unable to achieve pregnancy, while secondary infertility is to achieve pregnancy at least once in the past. According to the study; The presence of EFCAB5 is necessary that the movement is effective and directed in the right direction. If this protein is disrupted, even if the whip exists, its movement will not be sufficient, and the chances of the sperm in the fertilizer of the egg will therefore decrease. The lead researcher, Hauteng Wang, explained that the structure of the whip is very complicated and contains ‘radial thorns that control the movement’ and CFAP9 are part of these thorns, and it is related to infertility in humans, but that was not the reason for this. “The sperm of these mice -crap in the formation of the whip, which led to infertility of men. The molekeepers help scientists identify protein or molecules near a specific protein in the cell. In traditional ways, making it a powerful tool to understand the complex networks that control the self -function. the specialized movement of sperm.