Scientific innovation can relieve sick children of "Berlin's heart"

In a recent scientific study, a medical innovation has been found that can help children grow a heart in a “waiting period”, perform the hospital operation, stay at home and practice their regular activities. According to the results of the study, published in the Journal of Heart and Long Transplantation, the new innovation is a small pump that can be grown for this purpose for children, and promising results have shown in the first phase of clinical trials led by Stanford University of Medicine. The apparatus, which is a new type of ventricular aid devices, is surgically attached to the heart to increase blood pump in individuals with heart failure, allowing time to find a donor heart. The new pump, called Jarvik 2015, is slightly larger than the AA battery, and can be planted in children with a weight of about 26 kg, and it can block an important gap in caring for children’s heart transplanting, and if the early results are confirmed in a greater experience of the apparatus, it can be easier for young children and their families. Children’s heart failure and heart failure in children represent unique challenges, and often require urgent interventions such as heart transplant, but the shortage of donor organs, and the need for long periods of time in hospital while waiting for the appropriate congruence of major obstacles in the care of heart transplantation for children. To meet these challenges, a plantable heart pump is developed to provide mechanical support to patients’ hearts, which allows children to wait for the transplant instead of the hospital. The experience of the new plantable heart pump included seven children with heart failure, all of which are candidates for heart transplants to determine the safety and effectiveness of the apparatus in patients of children. Among the seven children who acquired the new heart pump eventually underwent six of them successful heart transplants, and one of these children was a great improvement in the heart function, which led to the need to completely need the process of heart transplant. These results shed light on the ability of the new device to bridge the gap in the care of heart transplant for children by providing effective mechanical support while waiting for the hearts of donors. The successful execution of the cultivated heart pump in the first phase of human tests is a great progress in the heart disease of children; Not only does the device provide a promising solution for children waiting for heart transplants, but it also carries the ability to improve the results and quality of life for patients with heart failure. “Berlin’s heart” and in this context, the only ventricular aid system is currently available to support children with heart failure, which is a pump called ‘Berlin’s heart’, which is not implanted; Since it is large as a travel bag, the weight varies between 27 and 90 kg, depending on the style, and is linked to the child with two two -sized garden hoses. The Berlin pump is a fairly high risk; This can cause stroke and in most cases require hospitalization, which means that children carry hospitalization for months while waiting for the heart transplant. As a result, the burden on children waiting for the heart transplant is much higher than the burden on adults to whom the heart pump is planted, and who regularly come out of the hospital with similar diagnoses. “We are very grateful that we have a Berlin Heart Device, a Savior of Life, and although the ventricle aids for adults improve every contract, but in Pediatrics we use this technology from the sixties,” the lead author of the Christopher Monde study, a professor of Pediaters at Stanford university. Almond mentions that implanted ventricular aid devices have been available for adults for over 40 years. The new pump is not only proportional to issuing patients, but also tends to use safer and easier than external devices such as the “Berlin Heart” device; Patients can live at home, work or school, walk and cycle. Alund says that the delay in pediatric technology is a problem for other devices designed to help children with heart disease, and in Pediatrics in general “there is a big difference in medical technology available to children and adults, which is an important overall health problem that is fighting markets because cases such as heart failure in children are scarce.” Many fewer children need heart transplants compared to adults, which do not leave a mentioned incentive for medical devices to develop a mini pump for children. But the lack of a small apparatus to help the ventricles for children hinder the medical system, as children attached to the Berlin Hartbult have great medical accounts, and they can occupy the family of hospitals in specialized cardiovascular units, which can reduce the availability of this family to others. The complications of the ventricular aid device included the feasibility of the ventricular aid equipment, seven children with systolic heart failure, and this condition affects the largest pump room in the heart, which is the left ventricle, which pumps blood from the heart to all body parts. Six children were injured by the systolic heart failure caused by a disease called expansionist myocardial disease, where the heart muscle increases and weakens and does not pump blood properly. The heart of one of the children did not pump blood due to a full heart barrier caused by lupus, which is an auto -immune disease, and all children in the experiment are listed in the heart transplant list. The device was surgically planted for each child in the left ventricle, which is the largest pump room for the heart, and at the same time, each one began to take a remedy to prevent blood clots, and reduce the risk of stroke, and when they received the pumps, the children were between 8 months to 7 years and their weight ranged between 8 to 20 kilograms. And if the medical organizational organizational bodies agree to the new pump, the number of children nominated for use, each year, around the world, ranges from 200 to 400 children. The experiment has been evaluated whether the pump patients can support for at least 30 days without stopping the work, or causing a sharp stroke, and the researchers also collected safety and initial performance data to help them design a greater experience to obtain the potential food and medicine section. Although the pump is perfectly aimed at waiting for children at home for heart transplants because it was part of a clinical trial, participants underwent hospital surveillance until they received or recovered a heart transplant. The quality of life and the researchers follow blood pressure for the participants, a sign of blood clots and the risk of stroke, in addition to measuring hemoglobin levels to verify whether the pumps break the red blood cells, and to monitor patients in search of other complications. The average time when the children used the pump 149 days performed six children heart transplants and the healing of one child was restored. A few children had complications while using the new pump; The child whose heart recovered sustained a stroke (from a blood clot) when the heart became strong enough to pump blood, remove the pump, and the child continued to recover and stay alive. Another patient suffered from the failure of the right side of the heart and was transferred to the ‘Berlin heart’ pump and awaited the transplant. For most patients, complications have been controlled, and can generally be compared to what doctors expect as a child is attached to the “Berlin Heart” center. The questionnaires about the quality of life showed that most children were not upset about the apparatus, and that they did not feel pain from it, and that they could participate in most of the playing activities, and one of the families reported that her young child could maintain a greater amount of movement with the pump, compared to his older brother who had previously received support from the Berlin pump.