"Hidden War" .. How are cholera bacteria better than the "viruses"?

Researchers at the Federal School in Lausanne, Switzerland, have managed to remove the success of the success of the dangerous epidemic tribes of cholera bacteria to resist the viruses that attack it. The study published in “Nature Microbiology” Journal “magazine” Natural Microbiology has revealed advanced defense mechanisms that enable cholera bacteria to withstand the attacks of bacterial viruses, which can highlight the reason for spreading some epidemics. The research focused on the tribe responsible for the epidemic that hit Latin America in the nineties of the last century, as it revealed the existence of a unique genetic “defensive arsenal” that gives bacteria immunity to various types of viruses. A fierce microscopic war, and these results only highlight the ongoing development of bacteria, but have also changed the strategies of anti -epidemiology in the future. When we hear about cholera, most of us come to the mind of contaminated water and the tragic spread of the disease in fragile areas. But behind the scenes, the cholera bacteria fight a fierce microscopic war that can determine the global epidemic path. Cholera bacteria not only have antibiotics and public health procedures, but are constantly attacked by ‘male’, which are viruses that affect and eliminate bacteria, and these viruses not only affect the individual infection, but can determine the course of the outbreak of the epidemic. The “cholera” bacteria are noted that some types of malad gas play a role in reducing the size and duration of cholera outbreaks by targeting the “cholera” bacteria that cause the disease. Since the sixties of the last century, the tribes of “L. Tour” of the seventh wave of cholera (7pet) have led the disease worldwide in successive waves. In this evolutionary breed of arming, bacteria developed defense mechanisms to counteract this man. It should be noted that the ‘lore’ is an epidemic strain of cholera bacteria, and is characterized by the ability to spread and remain longer periods in the environment compared to classic strains, as it causes an infection that can be clinically less severe, but it is more infected, contributing to the widespread epidemics. This tribe also has genetic characteristics that enable it to withstand some males (viruses that attack bacteria), which increase their ability to continue and expand geographically. How can certain strains of cholera virus attacks avoid successfully? Can it improve the devastating effect on people? The most mysterious cholera epidemic said the researchers said that one of the most mysterious fascism occurred in the early 1990s, when the Peruvian epidemic of Cholera and large parts of Latin America, which caused the injury of more than a million people and caused the deaths of thousands. The responsible strains belong to a stem known as the WASA of Cholera bacteria. To this day, the reason behind this epidemic is still widely incomprehensible in Latin America. The new research conducted by scientists at the International Institute of Health, attached to the Federal School in Lausanne, unveiled one of the secrets of this tribe, saying that the WASA breed had gained several specialized bacterial immune systems, which enabled it to withstand various types of male, and perhaps this defense helped them in the EPIDE. be. The researchers analyzed the Peruvian cholera tribes from the 1990s to find out what the resistance to the reluctance is, especially the dominant virus, known as ICP1, which is believed to play a major role in reducing cholera outbreaks in Bangladesh. The study showed that the Peruvian tribes showed immunity to ICP1, while the other strains of the seventh wave were not immune to it. By removing specific parts of the DNA from the dynasty and entering its genes in other bacterial strains to test its function, the team identified two most important defense areas in the Washa dynamine in the so-called WASA-1, and the genetic island known as VSP-II. A bacterial immune system, and these areas contain specialized anti -relation systems that work together to create a bacterial immune system that can block viral infection. One of these systems, called Wonab, stimulates the response of a “failed infection” that kills the affected cells before the viruses increase, which sacrifices a few bacteria to save the largest bacterial society. This strategy differs from classic bacterial immune systems, such as modification and cutting systems that destroy the virus -DNA when it enters the cell. The researchers have also discovered two other systems, Gravab and VCDUA, which provide additional protection, as grewabs target chemically modified DNA viruses, a strategy that the male to camouflage uses, while vcdua works against various families of viruses, which offers various low protection. The wasa dynasty of cholera bacteria has an extensive arsenal of anti -mortal defense systems, enabling it to withstand a wide range of viruses, including the main virus ICP1. The researchers have pointed out that understanding how to resist the epidemic bacteria of viruses is very important, especially with the return of interest in “relief therapy” and the use of viruses to treat bacterial infections as an alternative to antibiotics, if it is bacteria, such as “cholera”, the method of ability to effect the disease can improve. The research also highlights the importance of studying interactions between viruses and bacteria in managing the outbreak of infectious diseases.